Design at the nanoscale. In collaboration with world-class researchers and industry experts, Project NanoDesign aims to create the new generation of CAD tools to enable the design and manufacturing of nanoscale structures with the goal to accelerate the adoption of DNA nanotechnology and continue to push boundaries in research and application.
DNA nanotechnology is an exciting field of research where structures and machines are designed and assembled using DNA for use in therapeutics, research, and fabrication. “DNA origami” is a method in DNA nanotechnology where DNA folds into two- and three-dimensional structures at the nanoscale (10^-9m). It involves folding a single long strand of DNA into a shape by using many smaller "staple" strands to secure its folds. DNA origami is a powerful tool used in a variety of applications in therapeutics, research, and fabrication. Researchers are designing drug-containing DNA capsules directly targeting cancerous cells, shape-shifting DNA nano-machines with hinges and slider joints, and DNA nanoscale walkers able to carry and deposit materials along a minute assembly line.
In order to better understand the barriers faced by researchers trying to advance this field of science, the Bio/Nano Research group set out to ‘Imagine, Design, and Create’ the Autodesk ‘A’ logo in DNA. The design is visualized in Autodesk Research Molecule Viewer, assembled, and observed using atomic force microscopy magnified approximately 250,000 times.
In collaboration with industry and academic leaders, Project Nanodesign leverages Autodesk’s award-winning expertise in designing and manufacturing at the human scale, and bring it to the nanoscale.
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Cornelia Scheitz, Larry Peck, Eli Groban (2018)Biotechnology software in the digital age: are you winning?
Joseph Schaeffer, Michael Zyracki, Andrew Kimoto, Malte Tinnus, Yann Bertaud, Dion Amago, Florencio Mazzoldi, Merry Wang (2015)3D Visualization Of Cadnano And Protein Data Using A Cloud Streaming Framework For Web-Based Large Model Viewing