Azam Khan, Head of Environment and Ergonomics Research Group at Autodesk Research, delivered the closing keynote at the Advanced Digital Technology in Head & Neck Reconstruction Conference (ADT) in Beijing, China. In his keynote, Azam talked about the academic and industrial research consortium that has come together to work on the Parametric Human Project (PHP). The PHP has the goal of creating a complete data-driven morphological and physiological human model. Key research challenges in the PHP include anatomical data collection, data-driven ontological authoring, and a unifying theory for multiscale mixed-model multi-paradigm simulation. The application of advanced digital techniques in head and neck surgery has increased rapidly over the past decade. With this, the PHP vision for a goal-driven optimization system to help automate the designs needed for successful patient outcomes can contribute to the advancement of medical care.